A: DeSmuME is a new Nintendo DS emulator and the name is a play of words - DS Emu + ME (like FlashMe - firmware hack and PassMe mod-chip for DS)
The name DeSmuME derives from the popular use of ME in Nintendo DS products by homebrew developers. So DeSmuME would equal DSemuMe. Other popular uses of ME include:
LoadMe - a generic patcher for commercial DS roms that works with any GBA Flash Card,
PassMe - "mod-chip" using which takes authentication from an original DS card an allows execution of unauthenticated DS rom code from the GBA cartridge slot / GBA flash card.
FlashMe - a hacked firmware for DS that allows you to start code in DS mode from a flash card in the GBA slot.
WifiMe - are a set of a custom drivers and software by FireFly for RALink based wireless network cards enabling to boot homebrew code on DS via Nintendo Wireless Multiboot method.